Keep a second backup of your Data folder. If the USB fails, you lose your workspace and license cache. Sync it weekly to a cloud drive (but never run the app directly from Dropbox—it corrupts the registry redirect).
The version labeled claims to offer:
: Adobe does not produce or support "portable" versions of Illustrator. Official portable-like functionality was only briefly explored through "Adobe ThinApp," but never as a consumer product. Adobe.Illustrator.Portable.CS6-PortableApps.comFormat
: Used for designing logos, icons, and typography that can be scaled without losing quality. Packaging Files Keep a second backup of your Data folder