M-Audio Radium 49 is an "end of line" product, meaning official driver support has ceased for recent macOS versions. If you are using a modern Mac (macOS Catalina, Big Sur, Monterey, Ventura, or Sonoma), it will likely not work via a direct USB connection because it is not class-compliant and requires legacy drivers. Apple Discussions Compatibility Status Officially Supported: Up to macOS 10.8.5 (Mountain Lion). Last Known Working (with Drivers): Some users have successfully used the MIDI USB Driver v3.5.3 on macOS Mojave (10.14) or Yosemite (10.10.3). Incompatible:
Installation can be complex and may require disabling System Integrity Protection (SIP) or using Xcode to compile/install. 🔍 How to Check Connection
The Radium 49 allows you to split the keyboard into zones. This is useful for live performance.